Heart Damage Treatments Jacksonville FL

During a heart attack, vessels that supply blood to the heart become blocked, preventing enough oxygen from getting through. The heart muscle dies or is permanently damaged.

Anjali Sharma Pathak, MD
5251 Emerson St
Jacksonville, FL
Specialties
Cardiology
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Female
Education
Medical School: Gandhi Med Coll, Bhopal Univ, Bhopal, Mp, India
Graduation Year: 1989

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Venkata Sitaramaraju Sagi
(904) 396-5996
820 Prudential Dr
Jacksonville, FL
Specialty
Cardiology, Cardiovascular Disease

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Satish Rai Goel, MD
(904) 398-0125
836 Prudential Dr Ste 1700
Jacksonville, FL
Specialties
Cardiology
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Male
Education
Medical School: Univ Coll Of Med Scis, Univ Of Delhi, New Delhi, Delhi, India
Graduation Year: 1987

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Jose Alberto Ettedgui, MD
(904) 493-1610
1443 San Marco Blvd
Jacksonville, FL
Specialties
Cardiology
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Male
Education
Medical School: Univ De Carabobo, Fac De Cien De La Salud, Valencia, Venezuela
Graduation Year: 1982

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Paul H Dillahunt II, MD
(904) 396-5996
820 Prudential Dr Ste 112
Jacksonville, FL
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Cardiology
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Male
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Medical School: Oh State Univ Coll Of Med, Columbus Oh 43210
Graduation Year: 1973

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Carlos Leon-Barth
(904) 346-0707
3728 Philips Highway
Jacksonville, FL
Specialty
Cardiology

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George Foster Armstrong, MD
(904) 493-2291
1443 San Marco Blvd
Jacksonville, FL
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Cardiology
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Male
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Medical School: Duke Univ Sch Of Med, Durham Nc 27710
Graduation Year: 1962

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Shannon T Leu
(904) 720-0599
836 Prudential Dr
Jacksonville, FL
Specialty
Cardiovascular Disease

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Girish S Shroff, MD
(904) 396-5996
820 Prudential Dr Ste 112
Jacksonville, FL
Specialties
Cardiology, Internal Medicine
Gender
Male
Education
Medical School: J N M C Med Coll, Karnataka Univ, Belgaum, Karnataka, India
Graduation Year: 1980

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Paul William Farrell, MD
(904) 398-0125
836 Prudential Dr Ste 1700
Jacksonville, FL
Specialties
Cardiology
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Male
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Medical School: Oh State Univ Coll Of Med, Columbus Oh 43210
Graduation Year: 1973

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Heart Damage Treatments

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Doctors have been unable to help injured heart tissue renew itself after a heart attack -- until now.

During a heart attack, vessels that supply blood to the heart become blocked, preventing enough oxygen from getting through. The heart muscle dies or is permanently damaged.

But researchers at Children's Hospital Boston report progress toward someday being ale to regenerate heart tissue after a heart attack or heart failure and even in children who are born with congenital heart defects.

In a study on mice, they showed that neuregulin 1 (NRG1), a growth factor involved in the development of the heart and nervous system, can fuel heart-muscle growth and recovery of cardiac function when injected after a heart attack.

This is a significant development because coronary heart disease, which causes heart attack and angina, is the leading cause of death in America.

After birth, heart-muscle cells stop dividing and proliferating. But experts, led by Dr. Bernhard Kuhn and Kevin Bersell of the cardiology department at Children's, restarted the cell cycle with NRG1, spurring the heart-muscle cells to divide and make copies of themselves.

When the team injected NRG1 into live mice once a day for three months after the animals had heart attacks, heart regeneration increased and the pumping function improved, compared with untreated mice.

In addition, the NRG1-injected mice did not show some common aftereffects of heart failure.

The study, funded by the cardiology department at Children's Hospital Boston, the Charles Hood Foundation and the American Heart Association, found that cell growth does not have to come from stem cells. A report on the research appears in the July 24 issue of Cell.

"Although many efforts have focused on stem cell-based strategies, our work suggests that stem cells aren't required and that stimulating differentiated cardiomyocytes [heart-muscle cells] to proliferate may be a viable alternative," Kuhn, the study's senior investigator, said in a news release from the hospital.

More information

The American Heart Association has tips on maintaining a healthy heart.

SOURCE: Children's Hospital Boston, news release, July 23, 2009

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